Thermo Fisher Scientific TSPY1L Polyclonal Antibody
Human 및 Mouse 시료에 반응하는 TSPY1L 폴리클로날 항체로 Western blot에 적합합니다. Rabbit IgG로 제작되었으며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 완충액에 0.02% sodium azide가 포함되어 있으며, 냉장 또는 냉동 보관이 권장됩니다.
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Applications
- Western Blot (WB): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 13 amino acid peptide near the carboxy terminus of human TSPY1S |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at –20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551836 |
Product Specific Information
- A suggested positive control is A-20 cell lysate.
- PA5-34484 can be used with blocking peptide PEP-1526.
Target Information
Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome associated with gonadoblastoma.
In androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a nuclear steroid hormone receptor acting as a ligand-inducible transcription factor.
This suggests that TSPY1 functions as a repressor of cell proliferation in germ-cell tumors and possibly in normal gonadal cells during early development.
Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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