Thermo Fisher Scientific KIF3A Polyclonal Antibody
KIF3A 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 사용 가능. 인간, 마우스, 랫트에 반응하며, 고순도 IgG fraction 형태로 제공. 세포 내 수송 및 미세소관 관련 연구에 적합. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (KLH conjugated), corresponding to residues 682–701 of mouse KIF3A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5.3 mg/mL |
| Purification | IgG fraction |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_559814 |
Product Specific Information
Recommended positive controls: PC12, rat cerebellum.
Target Information
Kinesins are a large family of microtubule-dependent motor proteins responsible for the intracellular distribution of organelles, vesicles, and macromolecular complexes. Members of the heterotrimeric kinesin II family, including KIF3A, KIF3B, and KIF3C, mediate anterograde transport of membrane-bound organelles in neurons and melanosomes, as well as transport between the endoplasmic reticulum and the Golgi apparatus. KIF3A plays a crucial role in cilia and flagella morphogenesis, neurogenesis, and left-right axis determination. Loss of KIF3A function in mouse photoreceptors leads to apoptotic cell death, indicating its essential role in kinesin II-mediated transport for proper cell fate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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