Thermo Fisher Scientific PCSK1 Polyclonal Antibody
PCSK1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 인간, 설치류, 비인간 영장류 등에서 반응. 인슐린 생합성 및 전구단백질 처리 연구에 유용. 연구용으로만 사용 가능.
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Applications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate, Rabbit, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant, full length, rabbit PC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2283360 |
Product Specific Information
PA1-20317 detects PC1 in human, rat, and non-human primate samples.
Target Information
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. Members of this family process latent precursor proteins into biologically active products.
This encoded protein is a type I proinsulin-processing enzyme crucial for regulating insulin biosynthesis. It also cleaves proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin, and progastrin.
Mutations in this gene are associated with obesity and carcinoid tumors. Multiple alternatively spliced transcript variants have been described.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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