Thermo Fisher Scientific GALR2 Polyclonal Antibody
GALR2 단백질을 표적하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. IHC 및 IHC-P에 사용 가능하며, 인간 시료에 반응합니다. 항원 친화 크로마토그래피로 정제되었으며, 장기 보관 시 -20°C에서 보관 권장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 40 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Sheep |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (KLH conjugated) to the 7th transmembrane domain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2109152 |
Product Specific Information
By immunohistochemistry, OPA1-15410 detects GalR2 in formalin-fixed, paraffin-embedded human tissues.
Target Information
GalR2 expression has been documented widely in the brain and in peripheral tissues including small intestine, heart, kidney, and liver. Localization data from rat CNS indicate high levels of expression in dorsal root ganglia, amygdala, and Purkinje neurons.
G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members predicted to exist. All GPCRs share a structural motif of seven membrane-spanning helices and exist in both active and inactive forms. Activating ligands induce conformational changes leading to signaling via G-proteins and downstream effectors. Studies also show regulatory mechanisms that control GPCR activity, which are crucial for physiological responses and pharmacological research. GPCR-targeted drugs such as Zyprexa (Eli Lilly) and Claritin (Schering-Plough) demonstrate the clinical significance of this receptor family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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