Thermo Fisher Scientific RON Polyclonal Antibody
Human RON 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 4 µg/mL로 검증됨. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 세포 증식 및 이동 관련 연구용으로 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested at 4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from C-terminus of human RON |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_347196 |
Product Specific Information
OPA1-15590 antibody has been successfully used in immunohistochemistry procedures. By IHC, it detects the macrophage-stimulating 1 receptor (MST1R/Ron) in formalin-fixed, paraffin-embedded human tissues.
Target Information
MST1R (RON) is a receptor tyrosine kinase involved in cell proliferation and motility. It forms a membrane-spanning, disulfide-linked heterodimer from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits. Ligand binding induces tyrosine phosphorylation of the beta chain. MST1R/RON gene is mapped to 3p21, a region frequently mutated in small cell lung and renal carcinoma, and is implicated in epithelial cancer progression. Expression is documented in many normal human tissues, including colon, mouth, prostate, and testis, as well as in various cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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