Thermo Fisher Scientific Phospho-NFAT5 (Ser145) Polyclonal Antibody
NFAT5 단백질의 Ser145 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC 등 다양한 응용에 사용 가능. Human 및 Mouse 시료에 반응하며, 고순도 정제 및 안정적 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | – |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NFAT5 (Accession O94916), corresponding to amino acid residues around phosphorylated Ser145. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816864 |
Product Specific Information
This antibody detects endogenous levels of NFAT5 only when phosphorylated at Ser145.
Target Information
The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that collectively regulate the immune response. Four NFAT proteins (NFAT1–NFAT4) are encoded on separate genes and expressed as several splice variants. These proteins share limited sequence similarity with the Dorsal/Rel/NFkB family of transcription factors. NFAT5, a related protein, differs from NFAT1–4 in that it lacks many of the Fos/Jun contact sites and its subcellular localization is not calcineurin-dependent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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