Thermo Fisher Scientific Phospho-MPZL1 (Tyr260) Polyclonal Antibody
MPZL1 단백질의 Tyr260 인산화 형태를 특이적으로 인식하는 rabbit polyclonal antibody. Western blot 및 IHC(Paraffin)에서 검증됨. 고순도 정제, 1 mg/mL 농도, PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MPZL1 (Accession O95297), corresponding to amino acid residues around phosphorylated Ser260 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816868 |
Product Specific Information
Antibody detects endogenous levels of PZR only when phosphorylated at Ser260.
Target Information
Cell surface receptor involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and serves as a substrate for PTPN11/SHP-2. Acts as a major receptor for concanavalin-A (ConA) and participates in ConA-induced signaling involving Src family tyrosine-protein kinases. Isoform 3 may have a dominant negative role, blocking tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1 may regulate integrin-mediated cell motility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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