Thermo Fisher Scientific WSB1 Polyclonal Antibody
WSB1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot에 적합합니다. 인간, 생쥐, 랫트 반응성이 있으며, 항원 친화 크로마토그래피로 정제되어 높은 순도(>95%)를 제공합니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific WSB1 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000 dilution
Species Reactivity
- Human
- Mouse
- Rat
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length Human WSB1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.3 |
| Contains | 0.05% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718890 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum using epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.
Target Information
WSB1 (WD repeat and SOCS box-containing 1), also known as SWIP1, is a 421 amino acid protein containing one SOCS box domain and six WD repeats. It functions as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates ubiquitination and proteasomal degradation of target proteins such as DIO2. Overexpression of WSB1 has been implicated in pancreatic cancer progression, suggesting its role in carcinogenesis.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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