Thermo Fisher Scientific ATR Polyclonal Antibody
ATR 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 Immunoprecipitation에 적합. 인간 ATR(1675–1725 aa) 영역을 면역원으로 제작. 비결합(Unconjugated) 액상 형태로 제공되며, 4°C에서 보관. DNA 손상 반응 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 1675 and 1725 of human Ataxia Telangiectasia and Rad3-related (ATR, UniProt ID: Q13535-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
The ATR protein is a serine/threonine kinase and DNA damage sensor that activates cell cycle checkpoint signaling upon DNA stress. It phosphorylates and activates several proteins involved in the inhibition of DNA replication and mitosis, promoting DNA repair, recombination, and apoptosis. ATR is essential for fragile site stability and centrosome duplication. Defects in this gene can cause Seckel syndrome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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