Thermo Fisher Scientific ATR Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–5 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Mouse

Target Information

The ATR protein is a serine/threonine kinase and DNA damage sensor that activates cell cycle checkpoint signaling upon DNA stress. It phosphorylates and activates several proteins involved in the inhibition of DNA replication and mitosis, promoting DNA repair, recombination, and apoptosis. ATR is essential for fragile site stability and centrosome duplication. Defects in this gene can cause Seckel syndrome 1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.