Thermo Fisher Scientific RFC1 Polyclonal Antibody
RFC1 단백질을 인식하는 염소 유래 polyclonal 항체로, Western blot 및 면역침강(IP)에 적합합니다. 인산염 완충액(pH 7–8)에 보관되며, 항원 친화 크로마토그래피로 정제되었습니다. DNA 복제 및 수선 연구용으로 사용됩니다.
- 카탈로그번호
- A300141A
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific RFC1 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1100 and the C-terminus (residue 1148) of Human Replication Factor C subunit 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Replication factor C (RFC) is an essential DNA polymerase accessory protein required for multiple aspects of DNA metabolism, including replication, repair, and telomere maintenance.
RFC functions as a heteropentameric complex that recognizes primer-template DNA, binds to the primer terminus, and loads proliferating cell nuclear antigen (PCNA) onto DNA in an ATP-dependent manner.
All five RFC subunits share conserved RFC box sequences containing nucleotide-binding motifs.
RFC1, RFC2, RFC3, and RFC4 have consensus ATP-binding domains.
RFC2–RFC5 interact with Rad24, whereas RFC1 does not. RFC2, the third-largest subunit, exhibits ATP-binding activity critical for DNA replication and checkpoint control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.