Thermo Fisher Scientific CD154 (CD40 Ligand) Monoclonal Antibody (MR-1)
Thermo Fisher Scientific의 CD154 (CD40 Ligand) 단클론 항체(MR-1)는 마우스 CD154를 인식하며 WB, IHC, ICC, Flow Cytometry 등 다양한 분석에 적합합니다. 단클론 Armenian hamster IgG1 형식으로, 4°C에서 보관하며 기능적 차단(Blocking) 용도로 사용됩니다.
- 카탈로그번호
- MA110108
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 1 publication |
| Immunohistochemistry (IHC) | Assay-Dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-Dependent | - |
| Flow Cytometry (Flow) | 4 µg/mL | View 1 publication |
| Immunoprecipitation (IP) | Assay-Dependent | - |
| Functional Assay (Functional) | Assay-Dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Armenian hamster / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MR-1 |
| Immunogen | Activated mouse Th1 clone D1.6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153361 |
Product Specific Information
This antibody detects an extracellular epitope on murine CD154 / CD40L (CD40-ligand), a 39 kDa cell surface type II glycoprotein expressed predominantly on activated CD4+ lymphocytes.
Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
Functional Application: Blocking.
Target Information
CD40 Ligand (CD40-L), or CD154, is a membrane glycoprotein and differentiation antigen expressed on the surface of T cells.
The CD40 Ligand stimulates B cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines.
It has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes.
CD40 Ligand also co-stimulates proliferation of activated T cells, accompanied by the production of IFN-gamma, TNF-alpha, and IL-2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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