Thermo Fisher Scientific KIR2DL4 Monoclonal Antibody (mAb#33), PE
인간 KIR2DL4 항원을 인식하는 마우스 단클론 항체로, PE 형광으로 표지되어 NK 세포 표면 마커 분석에 적합합니다. Flow Cytometry에 사용 가능하며, PBS 기반 완충액에 보관됩니다. 4°C 암소 보관, 동결 금지.
- 판매단위
- pk
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Thermo Fisher Scientific KIR2DL4 Monoclonal Antibody (mAb#33), PE
Applications
- Flow Cytometry (Flow)
Tested Dilution: 20 µL / 1×10⁶ cells
Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | mAb#33 |
| Immunogen | NK3.3 cells and KIR2DL4-Ig fusion protein |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11155224 |
Additional Formats
- Unconjugated
- Alexa Fluor 647
- APC
- PE-Cyanine5
- Custom conjugation available
Product Specific Information
This antibody recognizes the extracellular portion of CD158d / KIR2DL4, a 45 kDa NK cell marker.
Cell surface expression and function of CD158d / KIR2DL4 depend on the genotype of individual donors.
Target Information
CD158d / KIR2DL4 is a member of the KIR family that shares structural features with both activating and inhibitory receptors.
It contains a cytoplasmic ITIM domain suggesting inhibitory function, but also a transmembrane domain similar to activating KIRs.
CD158d acts as an inhibitory receptor for peripheral and uterine NK cells, but ligation with soluble mAbs can activate IFN-γ secretion.
It binds both membrane-bound and soluble forms of its ligand HLA-G.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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