
Thermo Fisher Scientific SSX2 Monoclonal Antibody (OTI4D10), TrueMAB
SSX2 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot, IHC, ICC에 적합. Human 시료 반응성. 동결건조 형태로 제공되며 재구성 후 1 mg/mL 농도. 암 백신 연구 등 SSX 관련 연구에 유용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D10 |
| Immunogen | Full-length protein expressed in 293T cell transfected with human SSX2 expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, an additional desalting step is recommended.
(Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882)
Target Information
SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins, which may function as transcriptional repressors.
These proteins can elicit spontaneous humoral and cellular immune responses in cancer patients, making them potential targets for cancer vaccine-based immunotherapy.
SSX1, SSX2, and SSX4 genes are involved in the t(X;18) translocation found in all synovial sarcomas, resulting in fusion with the synovial sarcoma translocation gene on chromosome 18.
The resulting hybrid proteins are likely responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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