Thermo Fisher Scientific SSX2 Monoclonal Antibody (OTI4A11), TrueMAB
SSX2 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI4A11). Western blot, IHC, ICC 등 다양한 응용에 사용 가능. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도. 암 면역치료 연구에 유용한 항체.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4A11 |
| Immunogen | Full-length protein expressed in 293T cell transfected with human SSX2 expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins, which may function as transcriptional repressors.
They can elicit spontaneous humoral and cellular immune responses in cancer patients and serve as potential targets for cancer vaccine-based immunotherapy.
SSX1, SSX2, and SSX4 genes are involved in the t(X;18) translocation commonly found in synovial sarcomas, resulting in hybrid proteins with transforming activity.
Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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