
Thermo Fisher Scientific LIPG Monoclonal Antibody (OTI4C3), TrueMAB
인간 LIPG 단백질을 인식하는 마우스 단클론 항체로, IHC, ICC/IF, Flow Cytometry, IP 등에 사용 가능. 동결건조 형태로 공급되며, PBS 버퍼에 보존. HDL 대사 및 지질 효소 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C3 |
| Immunogen | Full length human recombinant protein of human LIPG produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
LIPG (Lipase G, Endothelial type) is an endothelial lipase and a member of the lipoprotein lipase gene family.
It is synthesized by endothelial cells and functions locally to modulate lipoprotein metabolism. Overexpression of LIPG can reduce HDL cholesterol levels, while deficiency increases HDL levels.
LIPG exhibits phospholipase activity and plays a role in lipid metabolism and vascular biology. It belongs to the triglyceride lipase family, characterized by a lid region providing substrate specificity.
LIPG hydrolyzes high-density lipoproteins, emulsifies triglycerides, and is essential for efficient digestion of dietary fats. It can also bind to heparin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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