Thermo Fisher Scientific LIPG Monoclonal Antibody (OTI3C7), TrueMAB
LIPG 단백질을 인식하는 Mouse 단클론 항체로 Western blot, IHC, ICC, Flow cytometry, IP에 사용 가능. Human 시료 반응성. Lyophilized 형태로 제공되며, 재구성 후 약 1 mg/mL 농도. 연구용으로 HDL 대사 및 지질 효소 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C7 |
| Immunogen | Full length human recombinant protein of human LIPG produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
LIPG (Lipase G, Endothelial type) is an endothelial lipase and a member of the lipoprotein lipase gene family. It is synthesized by endothelial cells and acts locally to modulate lipoprotein metabolism. Overexpression of LIPG reduces HDL cholesterol levels, whereas deficiency increases HDL levels in animals.
LIPG exhibits phospholipase activity and plays roles in lipoprotein metabolism and vascular biology. It is classified as a member of the TG lipase family based on sequence and structure, including a lid region that confers substrate specificity.
LIPG functions as a carboxyl esterase that hydrolyzes high-density lipoproteins, emulsifies triglycerides, aids in dietary fat digestion, and binds heparin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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