Thermo Fisher Scientific LIPG Monoclonal Antibody (OTI2D5), TrueMAB
LIPG 단백질을 인식하는 Mouse monoclonal antibody로, WB, IHC, ICC, Flow, IP 등 다양한 응용에 사용 가능. Human 시료 반응성, Lyophilized 형태로 제공되며, PBS buffer에 8% trehalose 포함. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D5 |
| Immunogen | Full length human recombinant protein of human LIPG produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
LIPG (Lipase G, Endothelial type) is an endothelial lipase and a member of the lipoprotein lipase gene family. It is synthesized by endothelial cells and acts locally to modulate lipoprotein metabolism.
Overexpression of LIPG reduces HDL cholesterol levels, while deficiency elevates HDL levels in animal models.
LIPG exhibits significant phospholipase activity and contributes to lipoprotein metabolism and vascular biology.
It is part of the TG lipase family, characterized by a lid region that confers substrate specificity.
LIPG functions as a carboxyl esterase that hydrolyzes HDL, emulsifies triglycerides, and is essential for dietary fat digestion and heparin binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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