Thermo Fisher Scientific PRKD3 Polyclonal Antibody
다양한 종(Horse, Human, Mouse, Rat)에 반응하는 PRKD3 폴리클로날 항체입니다. Western blot, IHC, ICC, ELISA 등 다양한 어플리케이션에 사용 가능합니다. Rabbit IgG 기반으로 Protein A 정제된 액상 형태이며, -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Horse, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human PRKD3, amino acids 345–550 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are involved in diverse cellular signaling pathways. They also serve as major receptors for phorbol esters, a class of tumor promoters. Each PKC family member has a distinct expression profile and functional role.
The protein encoded by this gene is one of the PKC family members, activated rapidly by agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, with nuclear accumulation enhanced upon activation. It can also be activated after B-cell antigen receptor (BCR) engagement, requiring intact phospholipase C gamma and other PKC family members.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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