Thermo Fisher Scientific Bestrophin 3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human VMD2L3. Recombinant protein control fragment (Product #RP-91144). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Bestrophin 3,uniProtId:Q8N1M1-2,ncbiNodeId:9606,antigenRange:322-462,antigenLength:668,antigenImageFileName:PA5-62985_Bestrophin_3_Q8N1M1-2_Rabbit.svg,antigenImageFileNamePDP:PA5-62985_Bestrophin_3_Q8N1M1-2_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649440

Product Specific Information

Immunogen sequence: VDEMHMSLPK MKKDIYWDDS AARPPYTLAA ADYCIPSFLG STVQMGLSGS DFPDEEWLWD YEKHGHRHSM IRRVKRFLSA HEHPSSPRRR SYRRQTSDSS MFLPRDDLSP ARDLLDVPSR NPPRASPTWK KSCFPEGSPT L

Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 81%.

Target Information

BEST3 belongs to the bestrophin family of anion channels, which includes BEST1, the gene mutant in vitelliform macular dystrophy (VMD), and 2 other BEST1-like genes, BEST2 and BEST4. Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.