Thermo Fisher Scientific URM1 Polyclonal Antibody
URM1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 액상 형태, 1 mg/mL 농도, PBS(glycerol 포함) 보존. URM1의 내인성 발현 검출에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human URM1 (Accession Q9BTM9), corresponding to amino acid residues I43–L93 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852399 |
Product Specific Information
Antibody detects endogenous levels of total URM1.
Target Information
Following the discovery of protein modification by the small, highly conserved ubiquitin polypeptide, a number of distinct ubiquitin-like proteins (Ubls) have been found to function as protein modifiers as well. These Ubls, including SUMO, ISG15, Nedd8, and Atg8, act as critical regulators of many cellular processes such as transcription, DNA repair, signal transduction, autophagy, and cell-cycle control. Dysregulation of Ubl-substrate modification and mutations in the Ubl-conjugation machinery have been implicated in various human diseases. URM1 is a ubiquitin-like modifier protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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