Thermo Fisher Scientific Phospho-JNK1/JNK2/JNK3 (Thr183) Polyclonal Antibody
JNK1, JNK2, JNK3의 Thr183 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 적합. MAPK 신호전달 연구에 유용하며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MAPK8 (Accession P45983), corresponding to amino acid residues around phosphorylated Thr183. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818307 |
Product Specific Information
This antibody detects endogenous levels of JNK1, JNK2, and JNK3 only when phosphorylated at Threonine 183.
Target Information
C-Jun N-terminal Kinase (JNK), also known as Mitogen-activated protein kinase (MAPK8), belongs to the MAPK superfamily of stress-activated protein kinases. These serine-threonine kinases are activated by various extracellular stimuli and mediate signal transduction from the cell surface to the nucleus.
JNK participates in numerous cellular processes, including proliferation, differentiation, transcription regulation, and development. JNK pathways are activated by stress and inflammatory signals, and the protein is expressed as ten isoforms due to differential mRNA splicing, with JNK1 and JNK2 being predominant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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