
Thermo Fisher Scientific IL3RA/CD123 Recombinant Rabbit Monoclonal Antibody (IL3RA, 2947R)
IL3RA/CD123 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단일클론 항체입니다. 인간 시료에 반응하며 IHC 및 Peptide Array에 사용 가능합니다. 고순도 Protein A/G 정제, 액상 형태로 제공되며 4°C 보관. 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 0.25–0.5 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | IL3RA, 2947R |
| Immunogen | Recombinant fragment of human IL3RA protein (around aa 26–171) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature (RT).
- For formalin-fixed tissues: Heat tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, then cool at RT for 20 min.
Target Information
IL-3Ra (Interleukin-3 receptor subunit alpha) is part of the type I cytokine receptor family. It forms a heterodimer with the common beta subunit (CDw131) to transmit the Interleukin-3 signal.
Heterodimerization of IL-3Ra and IL-3Rb chains is induced by Interleukin-3 and is essential for receptor activation.
IL-3Ra is overexpressed on acute myeloid leukemia (AML) blasts compared to normal hematopoietic cells, making it a potential therapeutic target.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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