Thermo Fisher Scientific MEPE Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 90-256 of human MEPE (NP_064588.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MEPE,uniProtId:Q9NQ76-1,ncbiNodeId:9606,antigenRange:90-256,antigenLength:525,antigenImageFileName:PA5-121235_MEPE_Q9NQ76-1_Rabbit.svg,antigenImageFileNamePDP:PA5-121235_MEPE_Q9NQ76-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.91 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914807

Product Specific Information

Positive test controls include: HepG2, Mouse liver, Mouse spinal cord, Rat brain, Rat liver. The target is usually found in the following locations: Secreted, extracellular matrix, extracellular space.

Immunogen sequence: FTNRQRLNKE YSISNKENTH NGLRMSIYPK STGNKGFEDG DDAISKLHDQ EEYGAALIRN NMQHIMGPVT AIKLLGEENK ENTPRNVLNI IPASMNYAKA HSKDKKKPQR DSQAQKSPVK SKSTHRIQHN IDYLKHLSKV KKIPSDFEGS GYTDLQERGD NDISPFS

Target Information

Matrix extracellular phosphoglycoprotein (MEPE), also known as osteoblast/osteocyte factor 45 (OF45), is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family. MEPE promotes renal phosphate excretion and modulates mineralization. It can be phosphorylated by secreted protein kinases. MEPE is expressed in osteoblasts, osteocytes and odontoblasts, and the expression has also been reported in numerous human tumor cell lines. It is a 525-amino acid protein with a calculated molecular weight of 58 kDa.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.