Thermo Fisher Scientific H4K8ac Recombinant Rabbit Monoclonal Antibody (RM201), ChIP-Verified
Histone H4K8ac 특이적 Rabbit Recombinant Monoclonal Antibody (RM201). ChIP 검증 완료로 높은 특이성과 재현성 제공. Western blot, ICC/IF, ELISA, ChIP, Luminex 등 다양한 응용 가능. Human 시료 반응성, Protein A 정제, 안정적 액상 형태.
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Thermo Fisher Scientific H4K8ac Recombinant Rabbit Monoclonal Antibody (RM201), ChIP-Verified
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.5–2 µg/mL |
| ELISA | 0.2–1 µg/mL |
| ChIP assay | 1–5 µg |
| Luminex (LUM) | 0.05–1 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RM201 |
| Immunogen | An acetyl-peptide corresponding to Acetyl-Histone H4 (Lys8) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 50% glycerol, 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C |
| RRID | AB_2815524 |
Product Specific Information
This antibody specifically reacts with Histone H4 acetylated at Lysine 8 (K8ac) and shows no cross-reactivity with other acetylated lysines in Histone H4.
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Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of eukaryotic chromosomal fibers. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer around which approximately 146 bp of DNA is wrapped, forming nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and helps compact chromatin into higher-order structures.
The histone H4 gene is intronless, lacks polyA tails, and contains a palindromic termination element. It is located within the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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(이미지 파일: MA5-33386_H4K8ac_P62805-1_Rabbit.svg, MA5-33386_H4K8ac_P62805-1_Rabbit_PDP.jpeg)
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