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Thermo Fisher Scientific Interferon gamma (IFNG) Recombinant Mouse Monoclonal Antibody (rIFNG, 4467)
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Recombinant mouse monoclonal antibody against human IFN gamma for IHC applications. High specificity and purity, expressed in HEK293 cells. Protein A/G purified, unconjugated liquid form, ideal for cytokine research and immune signaling studies.
- 판매단위
- pk
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Thermo Fisher Scientific 3458-MSM7-P1ABX Interferon gamma (IFNG) Recombinant Mouse Monoclonal Antibody (rIFNG, 4467) 100 ug pk판매 단위 pk
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Thermo Fisher Scientific · Thermo Fisher Scientific Interferon gamma (IFNG) Recombinant Mouse Monoclonal Antibody (rIFNG, 4467)
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | rIFNG, 4467 |
| Immunogen | Purified recombinant human full-length IFNG protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Interferon gamma (IFNγ, Type II interferon) is a macrophage activation factor produced primarily by T-lymphocytes and natural killer cells in response to antigens and cytokines.
- Dimeric glycoprotein (~45 kDa) composed of two 146 amino acid subunits
- Functions include antiviral and tumor antiproliferative activity, MHC induction, macrophage activation, and enhanced immunoglobulin secretion
- Acts via IFNγ receptor I and II through JAK-STAT signaling
- Highly species-specific; human IFNγ does not cross-react with mouse
- Upregulated by IL2, FGF basic, EGF; downregulated by vitamin D3 or DMN
- Mutations associated with aplastic anemia
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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