Thermo Fisher Scientific Human Lactoferrin Polyclonal Antibody, Biotin
Human Lactoferrin에 특이적인 Rabbit Polyclonal Antibody로 Biotin 결합형 제품. Western blot, IHC, ICC, ELISA 등 다양한 면역실험에 적합. 고순도 Affinity chromatography 정제, 안정적 액상 형태로 -20°C 보관.
- 카탈로그번호
- HLAC-BIOTIN
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length native protein purified human Lactoferrin |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Lactoferrin (LF) is an iron-binding glycoprotein composed of a single polypeptide chain (~80 kDa) folded into two homologous lobes, each capable of reversibly binding one ferric ion (Fe³⁺). LF is found in external fluids such as milk and mucosal secretions and is a major component of neutrophil secondary granules. It plays roles in iron homeostasis regulation, host defense against microbial infections, anti-inflammatory activity, cellular growth regulation, and protection against cancer development and metastasis.
Lactoferrin acts as a first-line defense against microbial infections by binding and removing Fe³⁺ from the environment and exhibits bactericidal and proteolytic activity. Three isoforms (LTF-α, LTF-β, LTF-γ) have been identified, and receptors for LTF are expressed in the gastrointestinal tract, macrophages, lymphocytes, neutrophils, platelets, and certain bacteria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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