Thermo Fisher Scientific Human Lactoferrin Polyclonal Antibody, FITC
Thermo Fisher Scientific의 FITC 결합 Human Lactoferrin Polyclonal Antibody는 인간 락토페린을 인식하는 토끼 유래 IgG 항체로, WB, IHC, ICC, ELISA 등 다양한 면역실험에 적합합니다. 형광 특성(FITC, 498/517 nm)으로 세포 및 조직 내 락토페린 검출에 유용합니다.
- 카탈로그번호
- HLAC-FITC
- 판매단위
- pk
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Thermo Fisher Scientific Human Lactoferrin Polyclonal Antibody, FITC
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length native protein purified human Lactoferrin |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Lactoferrin (LF) is an iron-binding glycoprotein composed of a single polypeptide chain (~80 kDa) folded into two homologous lobes, each capable of reversibly binding one ferric ion (Fe³⁺). It is found in external fluids such as milk and mucosal secretions and is a major component of neutrophil secondary granules.
Lactoferrin plays multiple roles, including:
- Regulation of iron homeostasis
- Host defense against microbial infections
- Anti-inflammatory activity
- Regulation of cellular growth and differentiation
- Protection against cancer development and metastasis
LTF acts as a first-line defense against microbes by binding and removing Fe³⁺ and exhibits bactericidal and proteolytic activity. Three isoforms (LTF-α, LTF-β, LTF-γ) have been identified, and receptors are expressed in the gastrointestinal tract, macrophages, lymphocytes, neutrophils, platelets, and some bacteria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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