Thermo Fisher Scientific Nectin 3 Monoclonal Antibody (04)
Human CD113/Nectin-3/PVRL3 단백질을 인식하는 Mouse IgG1 단일클론 항체로, ELISA 등 연구용에 적합합니다. 보존제가 없으며 장기보관 시 -20°C에서 보관 권장. 단백질 A로 정제된 고순도 액상 항체입니다.
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Applications
- ELISA (ELISA)
- Tested Dilution: 1:1,000–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 04 |
| Immunogen | Recombinant Human CD113/Nectin-3/PVRL3 Protein (Met1–Asp400) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786734 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human CD113/Nectin-3/PVRL3.
Target Information
Nectin-3 is an 83 kDa type I transmembrane glycoprotein belonging to the immunoglobulin supergene family. Nectin proteins are calcium-independent cell-cell adhesion molecules consisting of four members (nectin 1–4). They interact homophilically and heterophilically to form various junctions such as adherens junctions, synaptic junctions, and Sertoli cell-spermatid junctions.
Nectin-3 (PRR3) is predominantly expressed in testis and placental tissues, and interacts with afadin at cadherin-based junctions. The ectodomains of Nectin-3 and CD155 (Poliovirus Receptor) show strong affinity to each other.
Injection of antibody 103-A1 into seminiferous tubules disrupts actin filaments in Sertoli cells and causes exfoliation of maturing spermatids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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