Thermo Fisher Scientific N6-Methyladenosine (m6A) Monoclonal Antibody (A8F2)
N6-메틸아데노신(m6A)을 특이적으로 인식하는 단클론 항체로, RNA 메틸화 연구에 적합. ELISA 및 Dot blot 등 다양한 응용 가능. 마우스 IgG1 아이소타입, Protein A 정제. 장기 보관 시 -20°C에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA | 1:1,000–1:2,000 |
| Dot blot | 1:500–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A8F2 |
| Immunogen | m6A Small Molecule conjugated to OVA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090197 |
Product Specific Information
Product MA5-50598 was used in a Competitive ELISA.
Target Information
N6-methyladenosine (m6A), or methylation of the N6 position of adenosine, is a posttranscriptional modification of RNA. Due to a lack of analytical methods, N6-methyladenosine is poorly understood, but new evidence suggests that it is a very common base modification and an important physiological regulator.
N6-methyladenosine is markedly increased throughout brain development and is enriched near stop codons, microRNA-binding sites, and UTRs, indicating a fundamental role in gene expression regulation. It is also highly conserved between human and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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