Thermo Fisher Scientific Caspase 1 Polyclonal Antibody
Caspase 1 단백질을 검출하기 위한 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot, IHC, IP 등 다양한 응용에 사용 가능하며, 인간·마우스·랫트 반응성을 가집니다. 항원 친화 크로마토그래피로 정제된 고품질 항체로 연구용으로 적합합니다.
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Thermo Fisher Scientific Caspase 1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
| Immunoprecipitation (IP) | 2–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the internal segment of human Caspase 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Human liver tissue
- Cellular location: Cytoplasmic
Target Information
Caspases are a family of cysteine proteases divided into apoptotic and inflammatory subfamilies. Unlike apoptotic caspases, inflammatory caspases are involved in immune responses to microbial pathogens rather than cell death. Members include caspase-1, -4, -5, and -12, which activate proinflammatory cytokines such as IL-1β and IL-18. Caspase-1 was initially identified as an IL-1β-converting enzyme and later found to be a mammalian homolog of the C. elegans cell death gene ced-3, whose overexpression can induce apoptosis in fibroblasts.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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