Thermo Fisher Scientific ACVR2A Monoclonal Antibody (OTI1F2), TrueMAB
ACVR2A 단백질을 인식하는 Mouse monoclonal antibody로 Western blot과 IHC(Paraffin)에 적합. Human 시료에 반응하며, 액상 형태로 1 mg/mL 농도. Affinity chromatography로 정제되어 높은 특이성과 재현성을 제공.
- 카탈로그번호
- TA807404
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ACVR2A Monoclonal Antibody (OTI1F2), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 214–513 of human ACVR2A produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Activin A receptor kinase (ACVR2A) is a type II member of the TGF-beta family of receptor serine/threonine kinases.
ACVR2A participates in activin and myostatin signaling pathways (aliases: ACVR2, ACTRII).
These receptors are transmembrane proteins composed of a ligand-binding extracellular domain with a cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with serine/threonine kinase activity.
Type I receptors are essential for signaling, while type II receptors are required for ligand binding and for expression of type I receptors.
Upon ligand binding, type I and II receptors form a stable complex, leading to phosphorylation of type I receptors by type II receptors.
Type II receptors are considered constitutively active kinases.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.