Thermo Fisher Scientific RANBP1 Polyclonal Antibody
RANBP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합하며 인간과 생쥐에 반응. 고순도 항원 친화 크로마토그래피 정제, 액상 형태로 4°C 또는 -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–201 of Ran BP1 (Uniprot ID#P43487) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11152109 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji, mouse brain
- Predicted reactivity: Mouse (97%), Rat (97%), Xenopus laevis (84%), Pig (96%), Chicken (91%), Rhesus Monkey (99%), Bovine (88%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Ran/TC4-binding protein (RanBP1) interacts specifically with GTP-charged RAN.
RANBP1 encodes a 23-kDa protein that binds to RAN complexed with GTP but not GDP.
It does not activate GTPase activity of RAN but increases GTP hydrolysis by RanGAP1.
RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog.
In mammalian cells and yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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