Thermo Fisher Scientific IL12RB2 Polyclonal Antibody
IL12RB2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간에 반응하며 Western blot에 최적화. 고순도 항원 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:10,000
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 323–695 of IL-12 Receptor beta2 (Uniprot ID: Q99665) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11154134 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji
- Predicted reactivity: Dog (80%), Pig (80%), Bovine (80%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. Coexpression of IL12RB2 and IL12RB1 leads to formation of high-affinity IL12 binding sites and reconstitution of IL12-dependent signaling. Expression is up-regulated by interferon gamma in Th1 cells and plays a role in Th1 differentiation. Up-regulation is associated with diseases such as Crohn’s disease and leprosy, contributing to inflammatory response and host defense.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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