Thermo Fisher Scientific UBE2A Polyclonal Antibody
Thermo Fisher Scientific의 UBE2A Polyclonal Antibody는 인간 및 마우스 단백질에 반응하며, Western blot과 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 형태의 비결합 항체로, DNA 손상 복구 관련 연구에 유용합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- Publications: View 1 publication
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
- Publications: View references
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to amino acids 1–141 of Human UBE2A (UniProt ID: P49459-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris Glycine, pH 7, with 20% glycerol |
| Contains | 0.01% Thimerosal |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2547414 |
Product Specific Information
- Recommended positive control: Mouse brain
- Predicted reactivity: Mouse (100%), Rat (93%), Zebrafish (100%), Xenopus laevis (100%), Chicken (100%), Rhesus Monkey (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The modification of proteins with ubiquitin is a key cellular mechanism for targeting abnormal or short-lived proteins for degradation.
Ubiquitination involves three classes of enzymes:
- Ubiquitin-activating enzymes (E1s)
- Ubiquitin-conjugating enzymes (E2s)
- Ubiquitin-protein ligases (E3s)
The UBE2A gene encodes an E2 ubiquitin-conjugating enzyme required for post-replicative DNA damage repair.
Multiple alternatively spliced transcript variants exist, encoding distinct isoforms.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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