Thermo Fisher Scientific BCAR3 Polyclonal Antibody
BCAR3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB 및 IHC에 적합하며, 인간·생쥐·랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 시약으로 1 mg/mL 농도 제공. 냉장 또는 -20°C 장기 보관 가능.
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Thermo Fisher Scientific BCAR3 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | 16 amino acid synthetic peptide near the amino terminus of human BCAR3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 2–8°C에서 최대 3개월 보관, 장기 보관 시 -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551777 |
Product Specific Information
- Suggested positive control: HeLa cell lysate
- PA5-34425 can be used with blocking peptide PEP-1467
Target Information
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers can become anti-estrogen resistant. The breast cancer anti-estrogen resistance gene 3 (BCAR3) encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative SH2 domain, characteristic of cellular tyrosine kinase signaling molecules, and shares partial homology with CDC48.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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