Thermo Fisher Scientific MRPL18 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MRPL18 protein. Validated for IHC (Paraffin) with dilution 1:200–1:500. Purified by antigen affinity chromatography, supplied in PBS with 40% glycerol. Ideal for mitochondrial ribosomal protein research.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MRPL18 (Recombinant protein control fragment: Product #RP-94671) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644128 |
Product Specific Information
Immunogen sequence:
NGKVVVSAST REWAIKKHLY STRNVVACES IGRVLAQRCL EAGINFMVYQ PTPWEAASDS MKRLQS
Highest antigen sequence identity to the following orthologs:
- Mouse: 94%
- Rat: 92%
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and assist in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition, unlike prokaryotic ribosomes where this ratio is reversed. Mammalian mitoribosomes lack a 5S rRNA. The proteins comprising the mitoribosome vary significantly among species, making sequence homology recognition difficult.
This gene encodes a 39S subunit protein belonging to the L18P ribosomal protein family. Three polymorphic sites exist in this gene, one of which adds an extra amino acid near the N-terminus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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