Thermo Fisher Scientific MRPL18 Polyclonal Antibody
Human MRPL18 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot과 IHC(Paraffin)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 버퍼에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MRPL18. Recombinant protein control fragment (Product #RP-94670) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644127 |
Product Specific Information
Immunogen sequence:
MALRSRFWGL FSVCRNPGCR FAALSTSSEP AAKPEVDPVE NEAVAPEFTN RNPRNLELLS VARKERGWRT VFPSREFWHR LRVIRTQHHV EA
Highest antigen sequence identity to orthologs:
- Mouse: 77%
- Rat: 75%
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are essential for protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition, opposite to that of prokaryotic ribosomes. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA. The proteins comprising the mitoribosome vary significantly among species, both in sequence and biochemical properties. The MRPL18 gene encodes a 39S subunit protein belonging to the L18P ribosomal protein family. Three polymorphic sites exist in this gene, including one that causes an additional amino acid near the N-terminus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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