Thermo Fisher Scientific P2X6 Polyclonal Antibody
Human P2X6 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. PBS/glycerol buffer에 보존되며 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human P2RX6. Recombinant protein control fragment (Product #RP-95341). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645141 |
Product Specific Information
Immunogen sequence:
VTQIKELGNR LWDVADFVKP PQGENVFFLV TNFLVTPAQV QGRCPEHPSV PLAN
Highest antigen sequence identity to orthologs:
- Mouse: 94%
- Rat: 91%
Target Information
P2rx6 encodes receptors that are members of the ligand-gated ion channel family that open in response to extracellular ATP. Each P2rx6 receptor is composed of a trimer of subunits (P2X1–7), all sharing two transmembrane domains. The protein encoded by the P2rx6 gene belongs to the P2X receptor family, which are ATP-gated ion channels mediating rapid and selective permeability to cations.
P2rx6 is predominantly expressed in skeletal muscle and regulated by p53. The encoded protein associates with VE-cadherin at adherens junctions in human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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