Thermo Fisher Scientific CRISP2 Polyclonal Antibody
CRISP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Mouse 및 Rat 시료에 반응합니다. Western blot 및 ELISA에 적합하며, 고순도 Affinity Chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 22–243 of human CRISP2 (NP_003287.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.34 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855001 |
Product Specific Information
Immunogen sequence:
KDPAFTALLT TQLQVQREIV NKHNELRKAV SPPASNMLKM EWSREVTTNA QRWANKCTLQ HSDPEDRKTS TRCGENLYMS SDPTSWSSAI QSWYDEILDF VYGVGPKSPN AVVGHYTQLV WYSTYQVGCG IAYCPNQDSL KYYYVCQYCP AGNNMNRKNT PYQQGTPCAG CPDDCDKGLC TNSCQYQDLL SNCDSLKNTA GCEHELLKEK CKATCLCENK IY
Target Information
The cysteine-rich secretory proteins (CRISP) family consists of four proteins highly expressed in the male reproductive tract and associated with male fertility.
CRISP2 (also known as TPX1) is implicated in spermatid–Sertoli cell adhesion and sperm–egg fusion, in conjunction with CRISP1.
It regulates Ca²⁺ influx through ryanodine receptors (RYR), influencing acrosome reaction and sperm motility.
CRISP2 also binds MAP3K11 and localizes to the developing acrosome, suggesting a role in acrosome development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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