Thermo Fisher Scientific Protein APC Monoclonal Antibody (CC-1)

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

-

- -

Immunohistochemistry (Paraffin) (IHC (P))

5 µg/mL

-

Immunohistochemistry (Frozen) (IHC (F))

5 µg/mL

-

Immunohistochemistry - Free Floating (IHC (Free))

Assay-dependent

-

Immunocytochemistry (ICC/IF)

5 µg/mL

-

Miscellaneous PubMed (Misc)

-

View 1 publication 1 publication

Product Specifications

Published species

Not Applicable

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

CC-1

Immunogen

A recombinant protein consisting of amino acids 1-226 of APC. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Protein APC,uniProtId:P25054-1,ncbiNodeId:9606,antigenRange:1,antigenLength:2843,antigenImageFileName:MA1-25884_Protein_APC_P25054-1_House_mouse.svg,antigenImageFileNamePDP:MA1-25884_Protein_APC_P25054-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Storage conditions

4° C, do not freeze

Shipping conditions

Wet ice

RRID

AB_793034

Product Specific Information

MA1-25884 detects APC from human, mouse, and rat samples.

Target Information

This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.