Thermo Fisher Scientific NPPB Monoclonal Antibody (OTI7A8), TrueMAB
인간 NPPB 단백질(아미노산 27-102)에 특이적인 마우스 단클론 항체. Western blot 및 IHC(paraffin) 실험에 적합. 고순도 친화 크로마토그래피 정제. PBS/BSA/glycerol 완충액에 1 mg/mL 농도로 제공. 심혈관 연구 및 호르몬 관련 단백질 분석에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7A8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 27–102 of human NPPB produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene is a member of the natriuretic peptide family and encodes a secreted protein functioning as a cardiac hormone. The protein undergoes two cleavage events—one within the cell and another after secretion into the blood. Its biological actions include:
- Natriuresis
- Diuresis
- Vasorelaxation
- Inhibition of renin and aldosterone secretion
- Key role in cardiovascular homeostasis
A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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