
Thermo Fisher Scientific NPPB Monoclonal Antibody (OTI11C3), TrueMAB
인간 NPPB 단백질을 인식하는 Mouse IgG1 단클론 항체. Western blot에 적합하며, 고순도 친화 크로마토그래피 정제. PBS/BSA/glycerol 완충액 형태로 제공, -20°C 보관. 심혈관 연구용으로 적합.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI11C3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 27–102 of human NPPB produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene is a member of the natriuretic peptide family and encodes a secreted protein functioning as a cardiac hormone. It undergoes two cleavage events, one intracellularly and another after secretion into the blood. Biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and maintenance of cardiovascular homeostasis. Elevated levels in the bloodstream are indicative of heart failure. Mutations have been linked to postmenopausal osteoporosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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