Thermo Fisher Scientific MRCK alpha Polyclonal Antibody
Rabbit polyclonal antibody targeting human MRCK alpha for WB, IHC, and ICC applications. Recognizes amino acids 1671–1685 of MRCK alpha. Supplied as a liquid form at 0.25 mg/mL, stored at 4°C. For research use only.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | 1 publication |
| Immunocytochemistry (ICC/IF) | Assay-dependent | 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to amino acids 1671–1685 of human MRCK alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Wet ice |
| RRID | AB_11157634 |
Target Information
CDC42BPA (MRCKA) is a serine/threonine kinase involved in actin cytoskeleton assembly and organization. It contains three independent coiled-coil domains and an N-terminal region preceding the kinase domain, which mediate intermolecular interactions leading to MRCK alpha multimerization. The transautophosphorylation process regulates MRCK alpha catalytic activity. Binding of phorbol esters releases autoinhibition, enabling N-terminal dimerization and kinase activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(PA1-10038_MRCK_alpha_Q5VT25-1_Rabbit.svg 및 PA1-10038_MRCK_alpha_Q5VT25-1_Rabbit_PDP.jpeg 이미지 포함)
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