Thermo Fisher Scientific MRCK alpha Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200

-

Immunohistochemistry (Paraffin) (IHC (P))

-

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Immunocytochemistry (ICC/IF)

Assay-dependent

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Product Specifications

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide corresponding to the amino acids 1671-1685 of human MRCK alpha if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MRCK alpha,uniProtId:Q5VT25-1,ncbiNodeId:9606,antigenRange:1671-1685,antigenLength:1732,antigenImageFileName:PA1-10038_MRCK_alpha_Q5VT25-1_Rabbit.svg,antigenImageFileNamePDP:PA1-10038_MRCK_alpha_Q5VT25-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Storage conditions

4° C, do not freeze

Shipping conditions

Wet ice

RRID

AB_11157634

Target Information

CDC42BPA (MRCKA) is a serine/threonine kinase which functions in actin cytoskeleton assembly and organization. Three independent coiled-coil domains and the N-terminal region preceding the kinase domain are responsible for intermolecular interactions leading to MRCK alpha multimerization. The transautophosphorylation process is critical for regulation of MRCK alpha catalytic activities. Binding of phorbol esters to MRCK releases its autoinhibition, allowing N-terminal dimerization and subsequent kinase activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.