Thermo Fisher Scientific MEK1/MEK2 Polyclonal Antibody
MEK1/MEK2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. MAP kinase 경로 연구에 적합하며, 세포 성장 및 분화 관련 신호전달 분석에 활용됩니다. 액상 형태로 제공되며, 4°C에서 보관합니다.
- 카탈로그번호
- PA110034
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (coupled with KLH) derived from amino acid sequence 33–53 of human MAPK Kinase 1. The immunogen sequence is highly conserved within species (human, mouse, rat, hamster, bovine, etc.). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157258 |
Product Specific Information
This antibody reacts with intracellular antigens MEK1/2. MEK1 and MEK2 are integral components of the MAP kinase cascade, an important pathway for cell growth and differentiation.
Target Information
MEK1 (MAP Kinase Kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003).
In the brain, this pathway also plays a key role in synaptic processes (Adams and Sweatt, 2002).
Activated MEK1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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