Thermo Fisher Scientific CALU Polyclonal Antibody
CALU 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA에 사용 가능. Human, Mouse, Rat에 반응하며, Affinity Chromatography로 정제됨. -20°C 보관, 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 20–315 of human CALU (NP_001210.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.88 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2854890 |
Product Specific Information
Immunogen sequence:
KPTEKKDRVH HEPQLSDKVH NDAQSFDYDH DAFLGAEEAK TFDQLTPEES KERLGKIVSK IDGDKDGFVT VDELKDWIKF AQKRWIYEDV ERQWKGHDLN EDGLVSWEEY KNATYGYVLD DPDPDDGFNY KQMMVRDERR FKMADKDGDL IATKEEFTAF LHPEEYDYMK DIVVQETMED IDKNADGFID LEEYIGDMYS HDGNTDEPEW VKTEREQFVE FRDKNRDGKM DKEETKDWIL PSDYDHAEAE ARHLVYESDQ NKDGKLTKEE IVDKYDLFVG SQATDFGEAL VRHDEF
Target Information
Calumenin is a 315 amino acid Ca²⁺-binding member of the CREC, EF-hand protein family. It is a secreted protein localized in the lumen of the endoplasmic reticulum (ER) and Golgi apparatus, containing six Ca²⁺-binding EF-hand motifs. In the presence of Ca²⁺, Calumenin interacts with serum amyloid P component (SAP), potentially contributing to immunological defense and amyloidosis. It inhibits the vitamin K-dependent γ-carboxylation system and may play a role in thrombosis and wound healing through autocrine or paracrine mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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