Thermo Fisher Scientific Human PTRF Synthetic Peptide
Human PTRF 단백질의 카르복시 말단 19개 아미노산 서열을 기반으로 한 합성 펩타이드. Western blot 차단용으로 사용 가능하며, PA5-34522 항체와 함께 사용 권장. 고순도 정제, PBS/BSA 버퍼, -20°C 보관.
- 카탈로그번호
- PEP1565
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to a 19-amino-acid sequence near the carboxy terminus of human PTRF.
PEP-1565 can be used as a blocking peptide with polyclonal antibody PA5-34522.
For use as a blocking peptide in Western blot, incubate the peptide with an equal volume of antibody for 30 minutes at 37ºC.
Target Information
The polymerase I and transcript release factor (PTRF) enables the dissociation of paused ternary polymerase I transcription complexes from the 3′ end of pre-rRNA transcripts, regulating rRNA transcription by promoting the dissociation of transcription complexes and the re-initiation of polymerase I on nascent rRNA transcripts.
PTRF also localizes to caveolae at the plasma membrane and plays a critical role in the formation of caveolae and stabilization of caveolins. It translocates from caveolae to the cytoplasm after insulin stimulation and is implicated in lipid metabolism and insulin-regulated gene expression.
Mutations in this gene are associated with generalized lipodystrophy and muscular dystrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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