Thermo Fisher Scientific TEF Polyclonal Antibody
TEF 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot에 적합합니다. 인간에서 반응성이 확인되었으며, 마우스·랫·원숭이 등에서도 예측 반응성이 높습니다. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human TEF (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.91 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736695 |
Product Specific Information
- Positive Control: TEF-transfected 293T
- Predicted Reactivity: Mouse (97%), Rat (98%), Sheep (95%), Rhesus Monkey (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
TEF (thyrotrophic embryonic factor), also known as KIAA1655, is a 303 amino acid nuclear transcription factor belonging to the bZIP (basic region/leucine zipper) family and PAR (proline and acidic amino acid-rich) subfamily.
TEF binds DNA as a homodimer or heterodimer and transactivates the TSH beta promoter. It is broadly expressed in adults but restricted to the developing embryonic anterior pituitary gland. TEF accumulates according to a circadian rhythm and can inhibit cell growth by downregulating cytokine receptor beta chain expression.
Its functional domains are highly homologous with other PAR-bZIP subfamily members such as albumin D box-binding protein (DABP), human hepatic leukemia factor (HLF), and chicken vitellogenin gene-binding protein (VBP).
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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