Thermo Fisher Scientific TACR1 Polyclonal Antibody
TACR1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC 등 다양한 응용에 적합. 여러 종(Guinea pig, Human, Mouse, Rat)에 반응하며, 신경계 및 염증 관련 연구에 활용 가능.
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Thermo Fisher Scientific TACR1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:50 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Guinea pig, Human, Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Raised against a synthetic peptide at the C-terminus of rat NK-1 conjugated to bovine thyroglobulin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2200632 |
Product Specific Information
The target sequence has 92% sequence homology with canine.
Target Information
Tachykinin Receptor 1 (TACR1), a member of the Tachykinin Receptor subfamily, mediates phosphatidylinositol metabolism by tachykinin substance P (neurokinin 1).
It is associated with depression, anxiety, and stress regulation, and is involved in neuronal survival, cardiovascular, and respiratory functions.
TACR1 is implicated in rheumatoid arthritis and osteoarthritis progression.
Two variants are produced by alternative splicing.
Expression is mainly observed in brain, lymphocytes, nose, small intestine, and stomach.
ESTs have been isolated from brain and spleen libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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