Thermo Fisher Scientific AGR2 Monoclonal Antibody (GT5812)
AGR2 단백질을 인식하는 Thermo Fisher의 단클론 항체로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합합니다. 인간 시료에 반응하며, 예측 반응종은 마우스, 랫, 돼지 등입니다. 단백질 A로 정제된 액상 항체로, 4°C 단기 보관 및 -20°C 장기 보관이 권장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT5812 |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Anterior Gradient 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787201 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (93%), Rat (93%), Zebrafish (82%), Pig (96%), Rhesus Monkey (99%), Bovine (95%).
- Positive Control: MCF-7.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins involved in metastasis induction and p53 tumor suppressor inhibition. These proteins may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumors.
AGR2 is ubiquitously expressed and upregulated in prostate, breast, lung, renal, and endometrial carcinomas. Its expression is positively correlated with estrogen receptor (ER) and negatively correlated with epidermal growth factor receptor (EGFR).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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