Thermo Fisher Scientific H2BR79me1 Recombinant Rabbit Monoclonal Antibody (ST0430)

Applications and Tested Dilution

Product Specifications

Product Specific Information

This antibody is predicted to work in Western Blot at a dilution of 1:1,000.

Target Information

Eukaryotic histones are basic, water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer, consisting of two H2A-H2B dimers and two H3-H4 dimers, creating two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, which interacts with linker DNA between nucleosomes and mediates compaction into higher-order chromatin. Histones undergo posttranslational modifications primarily on their N-terminal tails, including methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination, and ADP-ribosylation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.